What is Exosome Therapy? Revealing The Power of Nanometric Particles
Exosome therapy is a relatively recent treatment method with promising results. These nanometric particles are now considered to be the most efficient options in treating particular conditions and health disorders.
What are exosomes?
Exosome therapy focuses on intercellular interaction which means that exosomes send the signals to cells acting like the messengers that bring definite information.
Exosomes are known to have lots of genetic information together with a set of various proteins, and they can easily reach their destination, which is generally a distant cell. This, in turn, will change the function of the target cell or its behavior.
Nowadays, these particles are widely used in diagnosing various diseases and in treatments. Much has changed since their discovery, and now the extracellular vesicles that were neglected and disregarded for their size are considered to have promising effects on our health.
How are exosomes isolated from stem cells?
Exosomes and stem cells are interconnected when it comes to exosome therapy. It’s important to highlight that extracellular vesicles are not cells despite having important genetic information and many types of proteins inside the membrane.
Owing to their ability to reach distant cells, carry important information, and change other cells’ function and behavior, extracellular vesicles are proven to have healing effects, not to mention other benefits that catch the interest of scientists.
Exosomes treatment has made it possible to obtain these vesicles from stem cells by means of ultracentrifugation. From a culture of stem cells, nanometric particles are removed from larger cells and other larger vesicles.
Ultracentrifugation is a process of isolating exosomes from cells which may take up to 30 hours. Experts dealing with that process are supposed to be specially trained people as the procedure is highly sensitive and requires a professional approach.
What is Exosome therapy?
Exosome therapy has been in use in recent years, and to understand this treatment, it’s important to delineate the extracellular vesicle and how it forms. In short, exosomes are particles released by cells.
Although they are known to be extracellular vesicles, meaning that these vesicles are outside the cell, their origin is endocytic – taking place inside the cell. Firstly, exosomes mature and get loaded inside the cell, and after some time, they fuse with the cellular membrane and are released into extracellular body fluid.
In this fluid, they travel to their target cell and when they reach their destination, they can interact with that target in different ways like combining or binding. Extracellular vesicles carry the important messages that trigger a cascade of effects or even change the cells’ function. Employing such motility and versatility, exosomes treatment has become a breakthrough in medicine.
What is Exosome therapy? Understanding the principles of treatment
Exosome therapy provides less intrusive treatment options and this is a great innovation for nanomedicine. Tiny particles floating in the body fluid may serve as mediators and messengers, and the practice of employing them in the treatment of disorders will substitute unneeded and costly alternatives. Thanks to extracellular vesicles’ uses and practical aspects, exosomes become an indispensable tool in medicine with much more purposes to be discovered.
Uses of Exosomes
Exosome therapy can be employed in the delivery of drugs to cells and organs of the body. They are known to pass the borders, and binding chemicals to them will make it possible for drugs to reach their destination in the body. Here are some other indications and uses of exosome treatment:
Immune system: Exosome therapy is one of the tools employed in treating conditions related to inflammatory responses. With exosomes, there are options of immune activation and suppression, depending on the condition being treated.
Hair loss and anti-aging: Exosomes derived from stem cells are proven to be efficient in treating hair loss and other conditions related to aging.
Neurodegenerative diseases: One of the uses of extracellular vesicles is treating and slowing down the effects of neurodegeneration that is caused by the death of some important cells of the central nervous system.
Cardiovascular system: Exosome treatment is used for cardiovascular disorders, especially in cases of heart attacks or MI. It is another option where extracellular vesicles are proven to have a healing effect on the damaged tissue.
What is an Exosome injection?
Exosomes are received through injections, but how do these shots work? The option of exosome injections comes with regenerating therapy where extracellular particles are directly administered to the specific location, a spot that is affected. Such shots are expected to speed up the intercellular interaction.
Receiving treatment with exosomes
What makes exosomes treatment preferable? It has been shown that stem cells may not function properly in terms of performing the expected tasks, as the advantage of extracellular vesicles is that they are capable of carrying information and content required for treatment, not to mention that they may easily pass barriers, like blood-brain one.
Exosomes and stem cells
When it comes to the exosomes treatment, these nanometric particles are obtained from the culture of stem cells to be employed in treatment. Ultracentrifugation is a must because of the size of the extracellular vesicles.
It’s not surprising that some experts interchange the idea of utilizing stem cells and exosomes thanks to their benefits. However, the core idea is to get the benefits without using the stem cells, but get them only with exosomes – vesicles ultracentrifuged in the lab. If you are wondering about both options or their differences, don’t hesitate to contact our team. Fill out the contact form online, and we’ll get back to you as soon as possible.
With the extracellular vesicles derived from stem cells, exosome therapy is used for treating aging symptoms as well as health issues caused by degenerative disorders. Such therapy option becomes revolutionary and a breakthrough one in medicine.